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Effect of different doses of butorphanol on postoperative analgesia after second cesarean section and its effect on newborns

Effect of different doses of butorphanol on postoperative analgesia after second cesarean section and its effect on newborns

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032449
Enrollment
Unknown
Registered
2020-04-28
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-09-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia of secondary cesarean section

Interventions

Butorphanol group A:Butorphanol 0.12mg/kg
Butorphanol group B:Butorphanol 0.15mg/kg
Butorphanol group C:Butorphanol 0.18mg/kg
sufentanil group:sufentanil 1.5ug/kg

Sponsors

Hu'nan Hengyang Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. We plan to choose the parturient who will have second cesarean section in the women and children center of Hengyang Central Hospital from May 2020 to may 2021; 2. Head position, singleton, 37-41w gestation, ASA grade I-II; 3. Delivery women aged 18-45 years old, 60-80 kg in weight and 155-170 cm in height; 4. Patients without contraindications of intraspinal anesthesia; 5. 500-600 parturients without history of opioid and local anesthetic allergy.

Exclusion criteria

Exclusion criteria: 1. The parturient who refused postoperative analgesia; 2. Patients with pregnancy complications; 3. Patients with chronic pain and low back pain; 4. Patients with spinal deformity; 5. Patients with a history of using painkillers; 6. The parturient with poor uterine contraction and bleeding greater than 1000ml.

Design outcomes

Primary

MeasureTime frame
Visual Analogue Score;nausea and vomiting;Ramsay sedation rating;Drug concentration in maternal milk;Neurobehavioral scores of NBNA neonates;

Countries

China

Contacts

Public ContactDianxiang Tan

Hu'nan Hengyang Central Hospital

dxtan22005@126.com+86 13875782871

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026