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Study on clinical cohort and serum biomarkers of patients with pulmonary tuberculosis-depression

Study on clinical cohort and serum biomarkers of patients with pulmonary tuberculosis-depression

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032447
Enrollment
Unknown
Registered
2020-04-28
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tuberculosis

Interventions

PTB-D group:N/A
PTB group:N/A

Sponsors

Shanghai Pulmonary Hospital
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients with clear consciousness, normal thinking and ability of language communication; 2. Patients who meet the diagnostic criteria of tuberculosis revised by respiratory branch of Chinese Medical Association in 2013; 3. Patients who meet DSM-V depression diagnosis standard of American Psychiatric Association diagnosis and Statistics Manual of mental disorders; 4. Patients with PHQ-9 depression scale >= 10 points; 5. Patients who obtain informed consent and voluntarily participate in the intervention plan; 6. Patients aged 18 or older and 65 or younger.

Exclusion criteria

Exclusion criteria: 1. Patients with history of mental illness, consciousness disorder, chronic respiratory failure, pulmonary encephalopathy and other serious complications; 2. Patients with thyroid diseases and other metabolic related diseases; 3. Patients who need continuous noninvasive or invasive ventilation, patients with hemodynamic instability; 4. Patients with heart and kidney dysfunction; 5. Patients with limb dysfunction; 6. Patients who cannot cooperate with the measurement; 7. Patients who fast for more than one day.

Design outcomes

Primary

MeasureTime frame
Metabolomics;

Secondary

MeasureTime frame
PHQ-9;nutrition status;

Countries

China

Contacts

Public ContactXue'e Fang

Shanghai Pulmonary Hospital

18918355605@163.com+86 18918355605

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026