Liver failure
Conditions
Interventions
Control group:Intervention: The control group received a daily dose of normal saline (0.9% NaCl) within 24 hours following their surgery, with this regimen continuing until day 7 after transplantation
Anticoagulant group:Patients in the anticoagulant group received a daily dose of 40 mg of enoxaparin within 24 hours following their surgery and continued this regimen until day 7 after transplantatio
Sponsors
West China Hospital, Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) All orthotopic deceased-donor liver transplantation p/µLatients aged between 18 and 70 years. (2) Signed informed consent and able to comply with the requirements of the program; if the patient is unable to sign the informed consent form, his/her legal guardian or representative must sign it.
Exclusion criteria
Exclusion criteria: (1) Autotransplantation, living donor, split and pediatric liver transplantation. (2) Other ongoing anticoagulative therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| major bleeding events within the first 90 days post-LT;venous thrombosis events within the first 90 days post-LT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Anti-Xa;PVT events within the first 90 days post-LT;DVT events within the first 90 days post-LT; | — |
Countries
China
Contacts
Public ContactYong Zeng
West China Hospital, Sichuan University
Outcome results
None listed