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Clinical study for automatic delineation of lung cancer radiotherapy target and organs in danger based on 4DCT and artificial intelligence

Clinical study for automatic delineation of lung cancer radiotherapy target and organs in danger based on 4DCT and artificial intelligence

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000032417
Enrollment
Unknown
Registered
2020-04-27
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Lung cancer

Interventions

experimental group:Intelligent sketch
Control group:manual sketch

Sponsors

Shanghai Pulmonary Hospital Affiliated to Tongji University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18 to 75 years; 2. Patients with kappa score >= 70 and weight loss = 12 weeks; 6. Patients with good blood function: serum hemoglobin >=100g/L, platelet >=100x10^9/L, neutrophil absolute count >= 1.5x10^9/L; 7. Liver function: serum bilirubin = 60ml / min; 9. Patients of childbearing age agreed to use reliable methods of contraception before entering the study, during the study and within 90 days after drug withdrawal; 10. The patients who voluntarily joined the study and signed the informed consent form had good compliance and cooperated with the follow-up.

Exclusion criteria

Exclusion criteria: 1. Patients who had received radical chest radiotherapy before; 2. Patients with pulmonary interstitial changes, COPD III and above; 3. Patients with postoperative radiotherapy for lung cancer; 4. Patients receiving concurrent radiotherapy and chemotherapy; 5. Patients with gemcitabine in the chemotherapy regimen before radiotherapy; 6. For patients with poor compliance in this study; 7. In the first 12 months of randomization, the patients with arteriovenous thrombosis events, such as cerebrovascular accident (including temporary ischemic attack, cerebral hemorrhage, cerebral infarction), deep vein thrombosis and pulmonary embolism, etc.; 8. Patients with a history of immune deficiency or other acquired, congenital immune deficiency diseases, or organ transplantation; 9. Other patients judged by the investigator not suitable for other situations in the study.

Design outcomes

Primary

MeasureTime frame
Accuracy;recall;Incidence of radiation pneumonia;

Countries

China

Contacts

Public ContactLiu Yu

Shanghai Pulmonary Hospital Affiliated to Tongji University

johnyuliu@sina.com+86 17717374119

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026