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Study on the Effect and Mechanism of Liangxuehuayuan Decoction in Increasing Efficacy and Reducing Toxicity in Radiotherapy of Esophageal Cancer

Study on the Effect and Mechanism of Liangxuehuayuan Decoction in Increasing Efficacy and Reducing Toxicity in Radiotherapy of Esophageal Cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032398
Enrollment
Unknown
Registered
2020-04-27
Start date
2020-05-15
Completion date
Unknown
Last updated
2021-07-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagus Cancer

Interventions

Sponsors

Jiangsu Provincial Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. The patient has a definite pathological and cytological diagnosis; 2. Peripheral white blood cells >= 4.0 x 10^9 / L, hemoglobin >= 90g / L, platelets >= 80 x 10^9 / L before radiotherapy; 3. KPS score >= 60 points, expected survival time> 3 months; 4. Liquid diet; 5. No esophageal perforation or active bleeding; 6. No serious heart, lung, liver and kidney function, coagulation dysfunction; 7. Cases in the experimental group still need to meet the Chinese medicine "yin deficiency poison" the diagnostic criteria for the syndrome of "heat syndrome" (prepared by Zhou Zhongying's "Chinese Medicine"): chest pain, poor sleep, low fever night sweats, or strong heat, thirst, dry stools, red tongue, yellow tongue coating, pulse count or large.

Exclusion criteria

Exclusion criteria: 1. Patients with mental illness or intellectual disability; 2. Poor compliance; 3. Allergic to experimental drugs; 4. At the same time participating in other clinical trials; 5. Combining other serious diseases, such as other tumors or serious infections.

Design outcomes

Primary

MeasureTime frame
OS, PFS, RFS and TTP;CR, PR, SD, PD;Cytokines;

Countries

China

Contacts

Public ContactYu Dahai

Jiangsu Provincial Hospital of Traditional Chinese Medicine

yudahaipumc@hotmail.com+86 13913982677

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026