Effect of Equivalent Doses of Fentanyl and Sufentanil on the Quality of Recovery After Gynecological Laparoscopic Surgery

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032396

Enrollment

Unknown

Registered

2020-04-27

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia for gynecological laparoscopic surgery

Interventions

Fentanyl group:Fentanyl group: intravenous injection of fentanyl 3-4ug / kg during anesthesia induction

intravenous injection of fentanyl 50ug during skin suture.

Sufentanil group:Sufentanil group: intravenous injection of Sufentanil 0.3-0.4ug / kg during anesthesia induction

intravenous injection of Sufentanil 5ug during skin suture.

Eligibility

Sex/Gender

Female

Age

20 Years to 55 Years

Inclusion criteria

Inclusion criteria: Aged 20-55 years old, BMI 18.5-24.9kg/m2, ASA I orII grade, interincisor distance >= 2.5cm, chin nail distance >= 6.5cm, head and neck mobility normal, Mallampati I or II grade.

Exclusion criteria

Exclusion criteria: 1. BMI >= 25kg / m2; 2. difficult airway; 3. history of airway hyperreactive disease in one month; 4. allergies of benzodiazepinesnon depolarizing muscle relaxants opioid drugs; 5. neuromuscular junction disease; 6. myasthenia gravis; 7. schizophrenia;severe depression, etc.; 8. cardiovascular disease and patients taking drugs that affect heart rate and blood pressure in the near future; 9. severe anemia, coagulation dysfunction, etc.

Design outcomes

Primary

Measure	Time frame
Recovery time (from drug withdrawal to mandatory eye opening);	—

Secondary

Measure	Time frame
Whether the patients choke the tracheal tube;Time of extubation of tracheal tube (time from drug withdrawal to extubation of tracheal tube);Ramsay score 5 minutes after extubation;5 minutes after extubation, whether the patient can move away from the operating table actively (can: need = 2 persons for assistance) can not: need > 2 persons for assistance);VRS and Ramsay scores 15 and 30 minutes after extubation;Modified birce questionnaire survey on the first and third day after operation;	—

Measure

Time frame

Whether the patients choke the tracheal tube;Time of extubation of tracheal tube (time from drug withdrawal to extubation of tracheal tube);Ramsay score 5 minutes after extubation;5 minutes after extubation, whether the patient can move away from the operating table actively (can: need = 2 persons for assistance) can not: need > 2 persons for assistance);VRS and Ramsay scores 15 and 30 minutes after extubation;Modified birce questionnaire survey on the first and third day after operation;

—

Countries

China

Contacts

Public ContactChunyuan Zhang

6 Chenggui Road, East District, Zhongshan, Guangdong, China

zhangchunyuan88888@163.com+86 13590835212

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026