Neuroinflammation in patients with postoperative cognitive dysfunction undergoing heart surgery after cardiopulmonary bypass

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000032324

Enrollment

Unknown

Registered

2020-04-25

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-09-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative cognitivection dysfunction

Interventions

case series:N/A

Eligibility

Sex/Gender

All

Age

14 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing heart surgery after cardiopulmonary bypass. 2. Preoperative MMSE score >= 23.

Exclusion criteria

Exclusion criteria: 1. Patients with preoperative dementia, brain atrophy and other uncooperative diseases. 2. With history of mental illness and serious visual and auditory disorders. 3. With history of Alzheimer's disease, Parkinson's disease or alcohol or drug dependence.

Design outcomes

Primary

Measure	Time frame
???????????2;NfL;S100B;C5A;	—

Secondary

Measure	Time frame
TNF-a;IL-6;IL-8;IL-10;NSE;	—

Countries

China

Contacts

Public ContactJi Fuhai

The First Affiliated Hospital of Soochow University

jifuhai@hotmail.com+86 0512-67780159

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026