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Effects of Hydromorphine on Clinical Effect and Stress Response of Ropivacaine Brachial Plexus Block

Effects of Hydromorphine on Clinical Effect and Stress Response of Ropivacaine Brachial Plexus Block

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032320
Enrollment
Unknown
Registered
2020-04-25
Start date
2020-05-06
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Replantation of severed finger

Interventions

experimental group:Brachial plexus block with 20 mL of 0.375% ropivacaine with 4 µg/kg hydromorphone
control group:Brachial plexus block with 20 mL of 0.375% ropivacaine

Sponsors

Affiliated Hospital of Nantong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: (1) Patients undergoing elective unilateral distal radius fracture surgery; (2) Aged 18 to 65 years; (3) Weight between 50 and 85 kg; (4) The American Society of Anesthesiologists status I to II.

Exclusion criteria

Exclusion criteria: (1) Combining basic diseases such as hypertension, diabetes, and coronary heart disease; (2) Suffer from severe mental illness; (3) History of unstable angina pectoris or myocardial infarction within 6 months; coronary angiography suggested severe stenosis of the main branches of the coronary arteries; (4) History of cerebral infarction or cerebral hemorrhage within 6 months; (5) Pregnant or lactating women; (6) People who are intolerant or allergic to local anesthetic and hydromorphinone; (7) Patients were judged unsuitable for inclusion in the trial.

Design outcomes

Primary

MeasureTime frame
IL-6;Cor;The onset time of brachial plexus block;Maintenance time of brachial plexus block;Use of analgesia within 24 hours;

Secondary

MeasureTime frame
VAS score of postoperative patients;

Countries

China

Contacts

Public ContactHuang SaiSai

Affiliated Hospital of Nantong University

sisy_007@163.com+86 13912268575

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026