Diabetic foot ulcer
Conditions
Interventions
Sponsors
Chongqing Orthopaedic Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-75 years, gender unlimited; 2. Patients diagnosed with diabetes mellitus and ulceration, which accords with the classical Wagner grading method of grade 1-3; Grade 0: no open lesions, but belongs to high-risk foot; Grade 1: superficial ulcer with skin penetration; Grade 2: deeper ulcer, including ulcers of joints and tendons; Grade 3: deep ulcer, abscess formation, tendon ligament tissue damage; Grade 4: local gangrene and bone destruction; Grade 5: total foot gangrene. 3. Patients who did not use immunosuppressive agents, or those whose doses of immunosuppressive agents remained unchanged recently; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. diabetic ketoacidosis, non-ketotic hyperosmolar coma patients; 2. women in lactation and pregnancy; 3. patients with allergic history or recent allergic diseases to multiple drugs; 4. patients with severe cardiopulmonary disease, cirrhosis, diabetic nephropathy or more, whose condition is still unstable after active medical treatment; 5. ulcers caused by malignant tumors; 6. patients with psychiatric diseases and ignoranceThose who can not express exactly; 7. those with poor compliance; 8. those who have participated in other clinical trials of new drugs in the last three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change of ulcer area;Clinical efficacy evaluation;Determination of inflammation-related indicators; | — |
Secondary
| Measure | Time frame |
|---|---|
| Observation of histochemical staining of granulation tissue; | — |
Countries
China
Contacts
Public ContactShen Kaiqin
Chongqing Orthopaedic Hospital of Traditional Chinese Medicine
Outcome results
None listed