The Effect of Parecoxib Sodium on Brain Edema and Inflammation in Patients With Supratentorial Brain Tumors: a Randomized Controlled Trial.

The Study of Parecoxib Sodium on Brain Edema in Patients With Supratentorial Brain Tumors: a Randomized Controlled Trial.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032300

Enrollment

Unknown

Registered

2020-04-25

Start date

2020-04-28

Completion date

Unknown

Last updated

2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Supratentorial brain tumor

Interventions

experimental group:Parecoxib sodium

control group:????

control group:normal saline

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients with Supratentorial brain tumors who meet the criteria of surgery and perform surgical treatment; 2. Aged 18 to 80 years; 3. Obtain the informed consent of the patient or family member.

Exclusion criteria

Exclusion criteria: 1. Patients with severe hepatorenal insufficiency; 2. Patients with peripheral vascular embolism, autoimmune diseases and severe digestive system diseases; 3. Patients who are not allowed to use parecoxib sodium.

Design outcomes

Primary

Measure	Time frame
Degree of brain edema;	—

Secondary

Measure	Time frame
mean arterial pressure;heart rate;temperature;VAS score;Neutrophils;C-reactive protein;prothrombin time;D-dimer;Time to stay in ICU;Incidence of vomiting;Incidence of DVT;NIHSS;GCS;	—

Countries

China

Contacts

Public ContactBaoguo wang

Sanbo Brain Hospital, Capital Medical University

wbgttyy@sina.com+86 13370185075

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026