traumatic brain injury
Conditions
Sponsors
Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force, China
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) The immediate family members signed the informed consent to participate in the experiment; (2) Aged 18-75 years old; (3) traumatic severe craniocerebral injury, GCS score between 3 and 8 points; (4) in line with the indications of decompression of bone flap.
Exclusion criteria
Exclusion criteria: (1) Non-traumatic brain injury, such as drowning, cardiac arrest, aneurysm rupture, spontaneous cerebral hemorrhage, etc.; (2) surgical contraindications: long-term use of anticoagulant drugs, more basic diseases, unstable vital signs upon admission, difficulty in tolerating surgery, multi-organ failure, etc.; Special injury sites, such as brainstem or ventricular hematoma; (4) contrast agent allergy, renal function is poor can not use contrast agent; (5) admission GCS 3 points, after emergency treatment without obvious improvement; (6) Emergency brain stem failure, such as respiratory heartbeat difficult to maintain; (7) Lack of consent from family members to participate in clinical trials or participation of patients in other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| rCBF;rCBV;MTT; | — |
Secondary
| Measure | Time frame |
|---|---|
| Velocity of blood flow in large intracranial vessels;Intracranial angiography; | — |
Countries
China
Contacts
Public ContactYuhai Wang
Department of Neurosurgery, 904th Hospital of Joint Logistic Support Force, China
Outcome results
None listed