osteoporosis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Perimenopausal criteria: aged 40-55 years, menopausal symptoms or irregular menstrual cycle to 1 year of menopause; 2. Early menopause criteria: 45-60 years old women, natural menopause 1-5 years.
Exclusion criteria
Exclusion criteria: 1. The population with history of malignant tumor, cardiovascular disease, serious chronic disease, endocrine disease or secondary osteoporosis; 2. People who used estrogen, calcitonin or bisphosphonate beyond 6 months; 3. People who drink and abuse drugs; 4. Eliminate MHT taboos.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| procollagen type 1 N-peptide;serum C-terminal telopeptide of type 1 collagen;dual energy X-ray absorptiometry;Osteoporosis related genes; | — |
Countries
China
Contacts
HangZhou Women's Hospital