severe brain injury patients
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. All patients admitted to ICU of our hospital were diagnosed as brain injury (stroke, brain injury) by skull CT examination, with GCS score of 3-8 and AgI level II and above(the score of gastrointestinal functional injury refers to the AGI diagnostic criteria developed by the European society of critical care medicine (ESICM)); 2. Aged >=18 years old; 3. The family members of the patients agreed to participate in the study.
Exclusion criteria
Exclusion criteria: 1. Severe trauma of chest and abdomen; 2. gastrointestinal motility drugs were used before admission; 3. local skin injuries at Zusanli, Zhongwan, Tianshu, Shangjuxu, xiajuxu, Zhongwan and other acupoints were not suitable for Electroacupuncture; 4. routine blood platelet count 2.0); 5. severe primary gastrointestinal diseases (such as massive alimentary tract bleeding, mechanical intestinal obstruction and intestinal perforation); 6. hemodynamic instability and shock were not controlled 24 hours after admission to ICU; 7. brain death.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 28-day mortality; | — |
Secondary
| Measure | Time frame |
|---|---|
| D-lac;diamine oxidase;lipopolysaccharides;motilin;gastrin;intra-abdominal pressure;bowel sounds;abdominal circumference;APACHE? score;Sequential Organ Failure Assessment score;Multiple Organ Dysfunction Syndrome score;duration of mechanical ventilation;duration of ICU stay;gastrointestinal function score;Incidence of hospital acquired pneumonia; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine