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Prospective Clinical Study of Evaluating the effects of virtual-reality-training on paretic upper limb motor function of stroke survivors from brain activation and motor control changes

Prospective Clinical Study of Evaluating the effects of virtual-reality-training on paretic upper limb motor function of stroke survivors from brain activation and motor control changes

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032245
Enrollment
Unknown
Registered
2020-04-24
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Stroke

Interventions

control group:VR training (such as Glasses-free 3D training,etc.), Multi-joint isokinetic testing and training
expiremental group:VR training (such as Glasses-free 3D training, etc.), Multi-joint isokinetic testing and training

Sponsors

The First Affiliated Hospital of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Patients with cerebral infarction or cerebral hemorrhage and motor dysfunction confirmed by CT or MRI examination (course duration >=1 month), aged 40-80 years. The diagnostic criteria are in accordance with the Chinese Medical Association Neurology Branch (2005) diagnostic criteria for cerebrovascular diseases. They are classified according to the Oxfordshire Stroke Project classification, that is, the Bamford classification, and the clinical treatment is performed according to the stroke scheme. At the same time do clinical records, including typing, course and functional stages, lesions, etc .; 2. right-handed patients (based on the Edinburgh Handedness Scales scale); 3. Brunnstrom stage = 3 stages; 4. Modified Ashworth score of hemiplegic elbow flexor in the range of 1-2; 5. Sufficient joint mobility on the hemiplegia side: elbow extension>=30 degree, wristextension >=20 degree, metacarpophalangeal joints extension>=10 degree; Sufficient passive range of motion of hemiplegic joint; 6. MMT grade of the hemiplegic upper limb >=3, have the ability to perform voluntary contraction of the upper limb; 7. No severe cognitive dysfunction (scored according to the Mini-Mental State Examination Scale); Intact auditory and visual sense to follow the instructions during test; 8. The patient signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Congestive heart failure; Malignant progressive hypertension; Respiratory failure; 2. With limb fractures; 3. History of mental illness or taking antipsychotic drugs; 4. Serious neglect of lateral space; 5. Cerebellum and brainstem injury.

Design outcomes

Primary

MeasureTime frame
fNIRS signals;High-Density Surface EMG signals;Torque signals;Kinematics data from motion capture system;

Secondary

MeasureTime frame
Action Research Arm Test, ARAT;Fugl-Meyer Assessment of Physical Performance;Modified Ashworth Scale, MAS;surface EMG;

Countries

China

Contacts

Public ContactLe Li

The First Affiliated Hospital of Sun Yat-Sen University

lile5@mail.sysu.edu.cn+86 020-87608536

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026