Nausea and vomit
Conditions
Interventions
control group:normal saline
Sponsors
Department of Anesthesiology, Nanjing Jinling Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients voluntarily sign the informed consent for this study; 2. Patients aged over 18 to 65 years old underwent elective general anesthesia for laparoscopic hysterectomy; 3. Patients weighing 50-65kg; 4. Patients undergoing elective laparoscopic hysterectomy; 5. Patients independently request analgesia before administration; 6. With no allergic disease, no constitution, no history of drug allergy, no history of non-malignant hyperthermia.
Exclusion criteria
Exclusion criteria: 1. Patients who have recently used monoamine oxidase inhibitors, opioids or psychoactive drugs; 2. With history of allergy to tramadol or propofol; 3. With history of epilepsy; 4. With hepatic or renal insufficiency; 5. Patients undergoing liver or kidney surgery; 6. Patients with heart valve disease or coronary artery abnormality; 7. With history of cerebral apoplexy; 8. With coagulation dysfunction; 9. With hypotension or shock; 10. With moderate to severe pulmonary dysfunction; 11. Preoperative pulse oxygen saturation (SPO2) below 90; 12. Pregnant or lactating women; Or subjects who had a pregnancy plan within 1 month after the trial (male subjects included); 13. Patients who had participated in the drug trial within 3 months prior to the trial (including the drugs in the trial); 14. Those who are deemed unfit to participate in the experiment by the anesthesiologist; 15. The researchers think there is any reason not to be included.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| nausea; | — |
Secondary
| Measure | Time frame |
|---|---|
| vomit;OAA/S;numerical rating scale, NRS;Adverse events; | — |
Countries
China
Contacts
Public ContactLi Renqi
Jinling Hospital, Jinling Clinical College, Nanjing Medical University
Outcome results
None listed