Intravascular intervention surgery
Conditions
Interventions
Group 5:saline
Group 1:Dexmedetomidine 0.3ug/kg.h
Group 2:Dexmedetomidine 0.4ug/kg.h
Group 3:Dexmedetomidine 0.5ug/kg.h
Group 4:Dexmedetomidine 0.6ug/kg.h
Sponsors
Renmin Hospital of Wuhan University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients who need general anesthesia for intravascular interventional operation and whose operation time is expected to be less than 4 hours; 2. Patients with aged >= 18 years, and ASA grade <= 3.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to dexmedetomidine; 2. Patients with morbid obesity (BMI > 35); 3. Patients with mental system diseases (such as schizophrenia, depression, etc.) and cognitive dysfunction; patients with history of epilepsy; patients with previous history of abuse of psychotropic drugs and narcotic drugs; 4. Patients with severe injury of liver and kidney function, ALT and / or AST > 1.5 times of the upper limit of normal value and creatinine value < 30; 5. Patients who participated in clinical studies of other drugs in recent three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the grade of cough during extubation; | — |
Countries
China
Contacts
Public ContactEyou Wang
Renmin Hospital of Wuhan University
Outcome results
None listed