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Prolonged GnRH agonist downregulation affects IVF-ET outcome in patients with endometriosis partially by regulating follicular microenvironment

Prolonged GnRH agonist downregulation affects IVF-ET outcome in patients with endometriosis partially by regulating follicular microenvironment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032174
Enrollment
Unknown
Registered
2020-04-22
Start date
2020-04-30
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis

Interventions

experimental group:Prolonged GnRHa downregulation
control group:Conventional luteal phase GnRHa downregulation

Sponsors

Department of Reproductive Medicine,Jinan Central Hospital Affiliated to Shandong University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: (1) All patients were diagnosed with stage III-IV endometriosis by laparoscopy or laparotomy. Pathological examination (based on the revised ASRM classification system) within two years before receiving fertility treatment; (2) 20-40 years old with a body mass index (BMI) of 18-25kg / m2; (3) normal uterus and normal menstruation (25-30 days), ovarian function is normal, FSH <10 IU / L; (4) resort to assisted reproduction technology (IVF-ET).

Exclusion criteria

Exclusion criteria: Infertility caused by other causes, such as congenital uterine abnormalities, Asherman syndrome, etc..

Design outcomes

Primary

MeasureTime frame
Clinical pregnace rate;Good embryo rate;Fertilization rate;—

Countries

China

Contacts

Public ContactBin Wu

Jinan Central Hospital Affiliated to Shandong University

wb0538@163.com+86 18668902156

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026