Effect of different level of hypercapnia on perioperative cerebral oximetry in small children: a randomized controlled trial

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000032145

Enrollment

Unknown

Registered

2020-04-20

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebral oxygen saturation

Interventions

PetCO2 normal level group:Protective ventilation strategy to maintain PetCO2 30-40 mmHg

PetCO2 medium level group:Protective ventilation strategy to maintain PetCO2 40-50 mmHg

PetCO2 high level group:Protective ventilation strategy to maintain PetCO2 50-60 mmHg

Eligibility

Sex/Gender

All

Age

0.5 Years to 12 Years

Inclusion criteria

Inclusion criteria: Infants who going to undertake selected surgery, aged 1~12 years old ASA classification between I to II.

Exclusion criteria

Exclusion criteria: (1) history of cerebral hypoxia; (2) congenital heart disease; (3) respiratory diseases such as pneumonia; (4) preoperative severe anemia; (5) preoperative use of antibiotics or nsaids.

Design outcomes

Primary

Measure	Time frame
cerebral oximetry;Area under curve of cerebral oxygen saturation;	—

Secondary

Measure	Time frame
arterial blood gas analysis;Venous blood gas analysis;MAP;SPO2;HR;PetCO2;	—

Countries

China

Contacts

Public ContactLi Yongle

Department of Anesthesiology, Guangdong Women and Children Hospital

muzirno@Hotmail.com+86 18026381651

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026