Skip to content

A randomized controlled study of Esketamine in patients undergoing transurethral ureteroscopy

A randomized controlled study of Esketamine in patients undergoing transurethral ureteroscopy

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032131
Enrollment
Unknown
Registered
2020-04-20
Start date
2020-06-19
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

transurethral ureteroscopy

Interventions

control group:Intravenous injection of propofol and sufentanil

Sponsors

The First Affiliated Hospital of Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 60 with unlimited gender; 2. The patients who are operated on by transurethral ureteroscopy; 3. Patients with ASA grade I or II; 4. 18.0 kg / m2 <= BMI <= 30.0 kg / m2.

Exclusion criteria

Exclusion criteria: 1. Patients who refuse to participate or are not suitable to participate in the test; 2. Patients who are allergic to propofol or esmketamine; 3. Patients with ketamine use contraindications such as severe refractory hypertension, cor pulmonale, hyperthyroidism, epilepsy, increased intraocular pressure, increased intracranial pressure or intracranial space occupying lesions, and history of cerebrovascular accidents; 4. Patients with obstructive sleep apnea hypopnea syndrome or BMI > 30 kg / m2 or with difficulty in respiratory tract; 5. Patients who had a history of drinking alcohol or taking psychoactive drugs or analgesics within 24 hours before operation; 6. Patients with a history of chronic pain; 7. Objects during pregnancy or lactation; 8. Epileptic patients; 9. Patients who use drugs that affect the central nervous system; 10. Patients with previous psychological diseases such as severe depression and history of mental and neurological diseases.

Design outcomes

Primary

MeasureTime frame
Anesthesia recovery time;

Secondary

MeasureTime frame
vital signs;Adverse reactions;Irritation of indwelling catheter;

Countries

China

Contacts

Public ContactDan Cheng

The First Affiliated Hospital of Zhengzhou University

fccchengd@zzu.edu.cn+86 371-66271232

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026