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Efficacy study on Transcranial magnetic stimulation based on video fluoroscopy and motor evoked potential in the treatment of dysphagia in convalescent stroke

Efficacy study on Transcranial magnetic stimulation based on video fluoroscopy and motor evoked potential in the treatment of dysphagia in convalescent stroke

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000032129
Enrollment
Unknown
Registered
2020-04-20
Start date
2020-05-01
Completion date
Unknown
Last updated
2020-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dysphagia during convalescence from stroke

Interventions

Group of cortical or subcortical dysphagia:Low frequency transcranial magnetic stimulation in healthy hemisphere
High frequency transcranial magnetic stimulation in damaged hemisphere
TMS pseudostimulation
Group of Brainstem dysphagia:Low frequency transcranial magnetic stimulation in healthy hemisphere

Sponsors

Rehabilitation Department of Huashan Hospital affiliated to Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 20-75 years old, regardless of gender; 2. The patients whose condition is stable within 1 month to 6 months and 1 week after the first stroke; 3. Stroke patients who have clear mind, no obvious cognitive impairment and can cooperate with examination and treatment; 4. Patients who need to have indirect aspiration symptoms such as salivation, choking and coughing during eating at the same time, or who have weakened tongue movement, larynx lifting, vomiting reflex, vocal cord paralysis, cough or wet voice when the patient drinks 5ml of water at the bedside, etc., indicating the clinical symptoms of dysphagia; 5. Right handed patients; 6. Patients who can sign the informed consent in person or on behalf of their immediate relatives.

Exclusion criteria

Exclusion criteria: 1. Patients with metal allogeneic implants (such as VP shunt, pacemaker, cochlear implant), patients with brain surgery history, epilepsy history, pregnancy patients, patients with severe speech disorder, neglect, depression, cognitive impairment (MMSE score less than 10 points), patients with serious alcohol or drug abuse history; 2. Patients with serious medical complications, pulmonary failure, heart function greater than grade II, uncontrolled hypertension, hyperglycemia, liver function problems, creatinine higher than normal, blood system diseases, etc; 3. Patients with tumor diseases; 4. Patients with estimated survival less than 6 months; 5. Patients with acute infectious diseases, such as severe pneumonia, tuberculosis, etc 6. Patients who participated in other clinical trials at the same time.

Design outcomes

Primary

MeasureTime frame
Resting Motion Threshold;Motor evoked potential;

Countries

China

Contacts

Public ContactJunta Wu

Huashan Hospital affiliated to Fudan University

junfawu2002@aliyun.com+86 21-52887820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026