Osteoporotic fracture
Conditions
Interventions
Gold Standard:Prospective study: Acute osteoporotic fracture of vertebral body was confirmed by X-ray, CT or MRI, especially MRI T2 STIR sequence.
Retrospective study: No vertebral fracture or signifi
IDEAL-IQ 
and 
X-ray, 
MRI 
imaging 
features.
Sponsors
The Affiliated Huai'an Hospital of Xuzhou Medical University / The Second People's Hospital of Huai'an
Eligibility
Sex/Gender
All
Age
20 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. One hundred and twenty healthy adults and 50 patients (25 cases for either thoracic or lumbar) with acute osteoporotic vertebral fracture (OVF) are about to be prospectively enrolled in this study. All the subjects should sign the informed consent. 2. Patients who underwent bone mineral density scan and other imaging examinations from January 2014 to March 2019 were retrospectively analyzed.
Exclusion criteria
Exclusion criteria: 1. Combined with bone tumors or tuberculosis in target spine; 2. Thyroid dysfunction or blood diseases; 3. Uncontrolled diabetes and kidney disease in the last 2 years; 4. Long-term use of drugs affecting bone metabolism, or long-term use of vitamin D and calcium supplements; 5. Continuous decline in mobility or forced long-term braking in the last 2 years; 6. Recent spinal fractures caused by severe violence such as car accidents or injuries; 7. Previous spinal fractures or severe spinal malformations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fat fraction;R2 STAR;Radiomics features;Serum nutrition and bone metabolism index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone Mineral Density (BMD);MR spectrum index;CT scan; | — |
Countries
China
Contacts
Public ContactBen Shan
The Affiliated Huai'an Hospital of Xuzhou Medical University / The Second People's Hospital of Huai'an
Outcome results
None listed