Thyroid nodules
Conditions
Interventions
Index test:Thin-layer 
liquid-based 
cell 
diagnosis,Hematoxylin 
Eosin,Immunohistochemistry,Reverse 
cription-Polymerase 
Reaction,Western 
Blot.
Sponsors
People's Hospital of Shapingba District, Chongqing
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients whose nodule diameter is >= 1cm and whose ultrasound shows solid hypoecho. 2. Patients whose nodule diameter is less than 1 cm but with malignant ultrasound signs (hypoechoic substance, irregular boundary, aspect ratio greater than 1, microcalcification, invasion of capsule). 3. Patients with nodule diameter > 0.5cm and high-risk clinical history (multiple endocrine neoplasia type II syndrome, head and neck radiotherapy history, family history of thyroid cancer, history of thyroidectomy or high level of calcitonin). 4. Patients with thyroid nodule of any size but with cervical lymph node metastasis (lymph node enlargement, disappearance of normal shape, unclear boundary between skin and medulla, internal microcalcification or liquefaction). 5. Patients with normal or elevated serum TSH level should be combined with ultrasound, while patients with decreased serum TSH should be combined with the results of thyroid nuclide scanning and ultrasound. In addition, ultrasound should be closely combined with the thyroid tumor (unexpected tumor, i.e. clinically untouched nodule found by imaging) which was accidentally found by positron emission tomography (PET). 6. The patients diagnosed as TBSRTC III cells by US-FNAC were treated with surgery to obtain pathological results.
Exclusion criteria
Exclusion criteria: Nil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Immunohistochemistry;SEN, SPE, ACC, AUC of ROC; | — |
Countries
China
Contacts
Public ContactYang Xi
Department of Ultrasound, People's Hospital of Shapingba District, Chongqing
Outcome results
None listed