Non-Small Cell Lung Cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients receiving lung cancer surgery (lobectomy, sleeve resection, pneumonectomy) with radical intention from May 1, 2020 to April 30, 2021 in our hospital; 2. Patients with non-small cell lung cancer confirmed by surgical pathology. If the disease is in pathologic complete remission after neoadjuvant therapy, cytopathology or histopathology must be confirmed as non-small cell lung cancer before operation; 3. Patients with incomplete resection (R1 or R2) indicated by surgical pathology, or incomplete resection indicated by surgical records, intraoperative judgment of surgeons, the first postoperative chest CT, or lymph node dissection failing to meet the requirements of at least three mediastinum stations, or patients with positive lymph nodes in the highest station confirmed by pathology; 4. Patients without supraclavicular lymph nodes metastasis or distant metastasis according to preoperative examinations; 5. Patients surviving at least 30 days after operation; 6. Within 90 days after operation, patients need to have post-operative baseline examination, at least chest CT (enhanced or not) and abdominal B-ultrasound; If no examination of brain is applied before surgery, brain MR/CT with contrast is needed within 90 days after surgery and need no signs of metastasis, plain scans can be considered for patients who do not tolerate contrast media; 7. The operation must be carried out in our hospital; Examinations and neoadjuvant/adjuvant therapy can be carried out in other hospitals, and there must be at least a paper report and discharge summary (if hospitalized); 8. Patients willing to sign an informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with pathologically confirmed mixture of small cell components by preoperative biopsy or surgical pathology; 2. Patients with cancer history within 5 years before the operation; 3. Patients with any lung surgical history (benign or malignant) before the lung cancer operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patterns of failure;2-year loco-regional recurrence free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| 5-year overall survival;Toxicity;Quality of life; | — |
Countries
China
Contacts
Shanghai Chest Hospital