Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
1.5ATA:1.5ATA HBO
2.5ATA:2.5ATA HBO
Control group:Routine treatment
Sponsors
Sixth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years old; 2. Patients suspected of having COVID-2019 pneumonia who also have one of the following etiological or serological evidence: (1) Real-time fluorescent RT-PCR detection of COVID-2019 nucleic acid positive; (2) viral gene sequencing, and Known novel coronaviruses are highly homologous; (3) Serum novel coronavirus-specific IgM antibodies and IgG antibodies are positive; serum novel coronavirus-specific IgG antibodies change from negative to positive or the recovery period is 4 times higher than the acute period and increased high; 3. Ordinary patients have fever, respiratory tract and other symptoms, and imaging shows pneumonia; 4. Severe patients meet any of the following criterias: (1) Shortness of breath, RR330 times / min; (2) At rest, refers to oxygen saturation 50% were managed as heavy. 5. No contraindications to hyperbaric oxygen therapy; 6. The patient and his family can sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. pregnancy or lactation; 2. having a history of major diseases such as disorders of liver, kidney, endocrine or hematological systems; 3. coagulation disorder; 4. explicit history of tumors; 5. having a history of malnutrition and cachexia; 6. contraindicated by HBOT, such as pneumothorax, poor pressure adjustment of the eustachian tube, and internal hemorrhage; 7. Critically ill patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Oxygenation index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activity endurance;IL-6 level;Blood routine biochemical indicators;LUNG CT scan;microparticle;CRP; | — |
Countries
China
Contacts
Public ContactShuyi Pan
Sixth Medical Center of PLA General Hospital
Outcome results
None listed