Postoperative Delirium
Conditions
Interventions
Deep sedation group:BIS:50~70
Light sedation group :BIS:71~90
Sponsors
Central Hospital of Zibo City
Eligibility
Sex/Gender
All
Age
80 Years to 100 Years
Inclusion criteria
Inclusion criteria: 1. ASA grade I~III; 2. Aged no less than 80 years; 3. no existed delirium determined by CAM method; 4. MMSE score >= 15.
Exclusion criteria
Exclusion criteria: (1) previous psychiatric (depression, schizophrenia) or neurological (stroke, transient ischemic attack, epilepsy, brain trauma, etc.) history; (2) severe visual and hearing impairment; (3) long-term use of sedative-hypnotic drugs and antipsychotic drugs; (4) excessive drinking;Alcohol dependence self rating > 2; (5) patients with pulmonary infection and COPD; (6) severe liver and kidney dysfunction (AST or ALT 1.5 times over normal, Cr or BUN over normal); (7) myocardial infarction or congestive heart failure within 6 months (NYHA grade IV); (8) allergic to local anesthetic drugs or propofol; (9) contraindications of nerve blocks such as puncture site infection, coagulation dysfunction, and peripheral neuropathy; (10) other fractures, bilateral hip fractures or previous history of hip fractures; (11) if the nerve block fails or the effect is poor, the patient changes to general anesthesia with auxiliary laryngeal mask or endotracheal intubation; (12) the operative time was more than 2.5 hours, or the intraoperative hemorrhage was more than 600ml.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| POD; | — |
Secondary
| Measure | Time frame |
|---|---|
| ADLs;VAS;BIS; | — |
Countries
China
Contacts
Public ContactJiguo Si
Central Hospital of Zibo
Outcome results
None listed