Liver cirrhosis
Conditions
Interventions
Sponsors
The Third Affiliated Hospital of Sun Yat-Sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Aged 18-70 years; 2. Patients were diagnosed liver cirrhosis by clinical, biochemical, imaging or pathological examination, the diagnostic criteria are in accordance with the "Guideline for Diagnosis and Treatment of Cirrhosis; 3. According to the guidelines of diagnostic criteria for chronic hepatitis b (2019 edition), those who meet HBsAg or (and) HBV DNA positive for more than 6 months, and show liver fibrosis or elevated liver enzymes caused by continuous infection of hepatitis B virus; 4. Healthy control group: physical examination report must include blood routine, liver function, biochemistry, blood lipids, preoperative screening, in which no obvious abnormalities are found; abdominal color ultrasound without fatty liver / liver fibrosis; no systemic disease; no platelet inhibitor, non steroidal anti-inflammatory drugs, LMWH or warfarin were taken in the past 14 days; 5. Signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Women in pregnancy; 2. Active bleeding, platelet transfusion, or use of platelet inhibitor, non steroidal anti-inflammatory drugs, LMWH or warfarin in the past 14 days; 3. A history of malignant tumors, uremia, rheumatic diseases that may affect coagulation function, or other obvious metabolic abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| platelet aggregation;FGF21, RBP4; | — |
Countries
China
Contacts
Public ContactXiuqing Wei
The Third Affiliated Hospital of Sun Yat-Sen University
Outcome results
None listed