Pregnancy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 190 cases of parturient women undergoing cesarean section under combined spinal and epidural anesthesia; 2. Subjects aged 18-40 and weighing 45-90kg; 3. American Society of anesthesiologists (ASA) grade I-II.
Exclusion criteria
Exclusion criteria: 1. Patients with severe liver and kidney dysfunction before operation; 2. Subjects with platelet < 50 x 10^9 / L before operation; 3. Patients with coagulation dysfunction; 4. Patients with intestinal function problems before operation; 5. Patients with history of severe bradycardia and heart block; 6. Patients with severe liver and kidney dysfunction; 7. Patients with mental disorders; 8. Patients with severe hypertension; 9. Patients who are allergic to dexmedetomidine and related ingredients; 10. Subjects with other contraindications of intraspinal anesthesia; 11. Other researchers think it is not suitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Exhaust time;Defecation time;nausea and vomit;bowel sound recovery time; | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative activity time;time of postoperative hospital stay;pain score;basic characteristics and intraoperative data; | — |
Countries
China
Contacts
The First Affiliated Hospital of Anhui Medical University