Pulmonary nodule or tumor
Conditions
Interventions
Sufentanil analgesia group:sufentanil-based analgesia
Non opioid analgesia group:dexmedetomidine-based analgesia
Sponsors
The First Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients who can sign informed consent; 2. Aged 18-70 years; 3. ASA class I-III; 4. Patients who scheduled to undergo thoracoscopic lobectomy.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to regional block technology (those with local anesthetic allergy, infection around puncture site and coagulation disorders); 2. Patients with a history of dependence on painkillers; 3. Dementia patients with any communication difficulties; 4. Patients who are allergic to the study drug; 5. Patients with heart rate < 50 times / min or type II-III atrioventricular block; 6. Patients with previous gastrointestinal ulcer or platelet abnormality; 7. Patients transferred to thoracotomy; 8. Patients who cancel the use of analgesia pump for various reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| A pain VAS during coughing at 24 h after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| first time to press pump;postoperative rest/ coughing VAS score;Postoperative opioid consumption;Times for press pump;exhaust time;Opioid-related side effects;Ramsay scores;Adverse events and complications(dizziness,hypotension, air leakage,lung infection,delirium,ect);Length of postoperative stay;Mortality;recurrence rate; | — |
Countries
China
Contacts
Public ContactXinqi Cheng
The First Affiliated Hospital of Anhui Medical University
Outcome results
None listed