B cell leukemia and lymhpoma
Conditions
Interventions
Case series:CART therapy
Sponsors
The First Affiliated Hospital of USTC (Anhui Provincial Hospital)
Eligibility
Sex/Gender
Male
Age
3 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Refractory or relapsed CD19 positive leukemia or lymphoma; 2. Aged 3 to 70 years; 3. ECOG score =55%; 6. Adequate liver function with AST <=5 ULN, ALT <=5 ULN; 7. Adequate kidney function with Scr<=1.6 mg/dl, BUN<=1.5 mg/dl; 8. Voluntary to enroll with signed consent form.
Exclusion criteria
Exclusion criteria: 1. Pregnant or nursing female patients; 2. Patients with infectious or viral diseases (HIV positive, syphilis, hepatitis b or c, etc.); 3. Patients undergoing treatment with Glucocorticoid; 4. Patients with allogeneic hematopoietic stem cell transplantation; 5. Patients undergoing with treatment against GVHD; 6. Patients with metastasis into CNS; 7. PLT<=50x10^9/L or Neutrophil<=750x10^6/L irrelevant to primary disease; 8. Patients received systemic chemotherapy 2 weeks or chemotherapy 3 weeks before blood collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Partial or complete remission; | — |
Countries
China
Contacts
Public ContactXingbing Wang
The First Affiliated Hospital of USTC (Anhui Provincial Hospital)
Outcome results
None listed