Novel Coronavirus Pneumonia (COVID-19)
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Laboratory confirmation of COVID-19 was performed at The First Affiliated Hospital of Yangtze University according to WHO interim guidelines,10 while ARDS diagnosis was performed according to the Berlin definitions. all COVID-19 patients who developed ARDS and who received mechanical ventilation. Included cases were confirmed ARDS patients according to their medical charts, had two consecutive arterial blood gas analysis (ABGA) with oxygenation index (OI), partial pressure of arterial oxygen (PaO2)/fraction of inspired oxygen (FiO2) =5 cm H2O), had bilateral radiographic opacities on computed tomography (CT) that could not be explained by effusions, pulmonary collapse, or nodules, and had respiratory failure that could not be explained by cardiogenic pulmonary edema.
Exclusion criteria
Exclusion criteria: Cases were excluded as they sustained a pulse oxygen saturation (SpO2) more than 95%. Additionally, patients with pulse oxygen saturation (SpO2) of more than 95% after oxygen therapy ( at a flow rate of 3 liters per minute) were excluded from the study. Patients with oxygenation index higher than 300 mmHg were also excluded from the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| partial pressure of arterial oxygen; | — |
Countries
China
Contacts
The First Affiliated Hospital of Yangtze University