Chronic liver disease
Conditions
Interventions
Chronic hepatitis B:antiviral therapy
Chronic hepatitis C:antiviral therapy
non-alcoholic steatohepatitis:drug treatment
liver cirrhosis:traditional Chinese medicine
liver cancer:traditional Chinese medicine
Healthy control group:Nil
Sponsors
The Third Hospital of Hebei Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Aged >= 18 years old. 2) Alcohol consumption per day is <= 20g for adult males, <= 10g for adult females, and drinking frequency is not more than 3 times a week. 3) In the past 1 year, the patients had no application history of traditional Chinese medicine, health care products or exposure history of environmental poisons such as formaldehyde, paint and hair colorants, et al. 4) Healthy volunteers without any disease; 5) Patients with chronic hepatitis or liver fibrosis, hepatocellular carcinoma, which were caused by hepatits B / C virus infection or non-alcoholic steatohepatitis. 6) Those who have not participated in other drug or therapeutic trials within 3 months.
Exclusion criteria
Exclusion criteria: 1) Patients with severe diseases with dysfunction of important organs such as heart, lung, kidney, brain and blood system. 2) Patients who are allergic to the ingredients of traditional Chinese medicine, or have experienced drug-induced liver injury.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| molecular diagnostic marker;effectiveness;differentially expressed genes; | — |
Secondary
| Measure | Time frame |
|---|---|
| safety; | — |
Countries
China
Contacts
Public ContactYuemin Nan
The Third Hospital of Hebei Medical University
Outcome results
None listed