Pregnancy waiting for delivery
Conditions
Interventions
experimental group:Intravenous injection of esketamine 0.5mg / kg.
Sponsors
The First Affiliated Hospital of Wannan Medical College
Eligibility
Sex/Gender
Female
Age
20 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1) parturient delivered by cesarean section; 2) Maternal aged 20 - 40 years; 3) gestational age >= 28 weeks = 10; 5) pregnancy without assisted reproductive means; 6) first parturient. 7) the subjects and their families voluntarily signed informed consent.
Exclusion criteria
Exclusion criteria: 1) patients with severe cardiovascular history such as myocardial ischemia, heart failure and arrhythmia), patients with cardiac pain (unstable angina pectoris) caused by insufficient blood supply of coronary arteries, or patients with myocardial infarction in the last 6 months; 2) patients with mental system diseases (schizophrenia, mania, bipolar abnormality, insanity, etc.), drug history and cognitive impairment; 3) patients with a history of asthma; 4) the good Ma score of the patients with respiratory tract management difficulties was grade IV; 5) AST and ALT > 2.5 x ULN, TBII >= 1.5 x ULN; urea or urea nitrogen > 1.5 x ULN, were higher than the upper limit of normal value in patients with severe heart, lung, liver and kidney disease or hepatorenal dysfunction before operation. 6) patients with abnormal blood coagulation PT or INR >= 1.5 x ULN, APTT >= 1.5 x ULN; 7) anemia or thrombocytopenia, Hb 100kg, height 180cm.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MAP, HR, CO, SvR and LCW;Propofol consumption;Awakening score record;Neonatal Apgar score;Cord blood gas analysis;Separated state scale CADSS;VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Nausea, headache, dizziness, blurred vision; | — |
Countries
China
Contacts
Public ContactChen Yongquan
The First Affiliated Hospital of Wannan Medical College
Outcome results
None listed