General Anesthesia
Conditions
Interventions
Group 1:Rimazoram
Group 2:Propofol
Sponsors
The First People's Hospital of Lianyungang
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. 18 <= age <= 65, gender unlimited; 2. Patients undergoing elective surgery; 3. ASA score is grade I or II; 4. Patients with 18 kg / m2 < BMI < 30 kg / m2; 5. Patients who clearly understand and voluntarily participate in the study and are willing to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients in emergency operation; patients in hypovolemia, shock or coma; 2. Patients who plan to use general intravenous anesthesia and need to combine other anesthesia methods, such as inhalation anesthesia and Epidural and subarachnoid anesthesia; 3. Patients with infectious heart diseases such as myocarditis or endocarditis or septicemia; 4. Uncontrolled hypertension, diabetes, heart failure, etc.; 5. Patients with abnormal liver function, AST and / or ALT >= 2.5 x ULN, TBIL >= 1.5 x ULN; 6. Patients with abnormal renal function, urea or urea nitrogen >= 1.5 x ULN, and creatinine > the upper limit of normal value; 7. Patients with mental system diseases (schizophrenia, mania, bipolar disorder, insanity etc.) or have a long history of taking psychoactive drugs, have cognitive dysfunction; 8. Pregnant or lactating women; 9. Patients who are allergic to benzodiazepines, opioids, propofol, muscle pines and other drugs, or who are allergic to or have contraindications to drug ingredients; 10. Other circumstances in which the researchers consider it inappropriate to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Success rate of anesthesia induction; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of hypotension during induction of anesthesia; | — |
Countries
China
Contacts
Public ContactXiaobao Zhang
Department of Anesthesiology, the First People's Hospital of Lianyungang
Outcome results
None listed