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A randomized, double-blind, placebo-controlled, multicenter post market clinical study on the efficacy of benzyl lysine eye drops in delaying early senile cataract

A randomized, double-blind, placebo-controlled, multicenter post market clinical study on the efficacy of benzyl lysine eye drops in delaying early senile cataract

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031790
Enrollment
Unknown
Registered
2020-04-10
Start date
2020-04-16
Completion date
Unknown
Last updated
2020-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

early period senile cataract

Interventions

experimental group: benzalalysine eye drops
control group:placebo

Sponsors

Zhongshan Ophthalmic Center of Sun Yat-Sen University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subjects who meet all of the following criteria may be enrolled in this trial: (1) 50-70 years old, willing to participate in the test, able to follow up on time; (2) ETDRS visual acuity chart test: corrected vision 0.3-0.7; (3) When the pupil reaches 8 mm after mydriasis, the lens cortex is turbid by slit-lamp microscopy, which is the initial stage; (4) Patients with bilateral cataract; (5) Exclude other eye diseases affecting corrected vision, such as corneal diseases, glaucoma, fundus diseases, etc; (6) No history of systemic or local treatment of cataract; (7) Voluntary participant and signer of informed consent.

Exclusion criteria

Exclusion criteria: If the subject meets any of the following criteria, the conditions for entering the test are not met: (1) Abnormal liver and kidney function; (2) Patients with serious cardiovascular and cerebrovascular diseases, malignant tumors and other diseases; (3) Patients with diabetic retinopathy and other fundus diseases; (4) With a history of mental illness; (5) Those who cannot be followed up on time; (6) Pregnancy, lactation or expectant pregnancy.

Design outcomes

Primary

MeasureTime frame
turbidity of crystalline lens under slit-lamp;BCVA;OQAS;

Countries

China

Contacts

Public ContactJian Ge

Zhongshan Ophthalmic Center, Sun Yat-Sen University

18057356628@189.cn+86 18057356628

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026