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Screening of biomarkers of severe community acquired pneumonia and its indication for glucocorticoid in the treatment of severe community acquired pneumonia

Screening of biomarkers of severe community acquired pneumonia and its indication for glucocorticoid in the treatment of severe community acquired pneumonia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031757
Enrollment
Unknown
Registered
2020-04-09
Start date
2020-04-03
Completion date
Unknown
Last updated
2020-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

pneumonia

Interventions

Experimental group:Hormone
Control group:Without hormone

Sponsors

Department of respiratory medicine, The Seventh Medical Center of PLA General Hospital (Predecessor of Army General Hospital )
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years old; 2. Conform the diagnostic criteria of CAP and SCAP in "diagnosis and treatment guidelines for adult community acquired pneumonia of China" (2016 Edition); 3. Chest CTshould be done in pneumonia patients; 4. With the exception of fungus pneumonia, aspiration pneumonia, pulmonary tuberculosis.

Exclusion criteria

Exclusion criteria: 1. Expect the patients of diabetes, chronic pulmonary disease, severe hypertension, Acute cardiovascular and cerebrovascular diseases, cardiac failure, connective tissue disease, chronic renal failure; 2. Pregnant women; 3. Non infectious pulmonary exudative disease; 4. Lung tumor or combined with lung tumor; 5. Transaminase 2 times higher than normal; 6. Special treatment history in recent half a year(Such as radiotherapy and chemotherapy, surgery, biotherapy, immunotherapy); 7. Severe allergic disease; 8. infectious diseases in the past 90 days; 9. contraindications of glucocorticoid application.

Design outcomes

Primary

MeasureTime frame
IL-6;C5a;

Countries

China

Contacts

Public ContactJiandong LI

The Seventh Medical Center of PLA General Hospital (Predecessor of Army General Hospital)

ljdyz@hotmail.com+86 10 84008044

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026