Major Depressive Disorder
Conditions
Interventions
case series:Escitalopram
Sponsors
Beijing Anding Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Out-patient patients aged 18 ~ 65 (including 18 and 65 years old), regardless of gender; 2. Comply with the diagnostic criteria for major depressive disorder (MINI5.0.0) of the diagnostic and statistical manual of mental disorders (dsm-iv), with no psychotic symptoms; 3. This episode has not been treated with antidepressant system or no antidepressant treatment in the past 14 days; 4. Primary school education or above, able to understand the content of the scale; 5. Able to use an android smartphone and wear a smart bracelet as required; 6. Patient signs the informed consent.
Exclusion criteria
Exclusion criteria: 1. Previous clear manic or hypomanic episodes; 2. Previous diagnosis of bipolar disorder, schizophrenia, schizoaffective disorder and mental disorders associated with other diseases; 3. Patients with previous alcohol and drug dependence and acute poisoning history; 4. Patients who currently have a serious risk of suicide; 5. Have independent sleep disturbances (eg, obstructive sleep apnea, narcolepsy, bruxism, periodic limb movement disorders, restless legs, and other sleep behavior abnormalities); 6. At present, there are diseases that seriously affect heart rate and respiratory monitoring, such as acute onset of chronic obstructive pulmonary disease, acute onset of asthma, sinus tachycardia, sinus bradycardia, arrhythmia and other diseases; 7. Patients who have been previously ineffective or allergic to escitalopram; 8. At present, some researchers with severe physical diseases consider it inappropriate to be enrolled in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| HAMD-17 total score and item score;HAMA total score and item score;PHQ-9 total score and item score;sleep duration;body temperature;heart rate;step number;the variety of motion track;step number;smartphone usage behavior; | — |
Countries
China
Contacts
Public ContactFeng Lei
Beijing Anding Hospital Capital Medical University
Outcome results
None listed