Effect of rTMS on freezing of gait in Parkinson's disease and its neural mechanism

Effect of rTMS on freezing of gait in Parkinson's disease and its neural mechanism.

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000031717

Enrollment

Unknown

Registered

2020-04-08

Start date

2020-04-20

Completion date

Unknown

Last updated

2020-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

experimental group:rTMS on M1 area

control group:rTMS on occipital lobe

Eligibility

Sex/Gender

All

Age

40 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Idiopathic PD patients. 2. Presenting with FOG. 3. The medication does not change within 3 months.

Exclusion criteria

Exclusion criteria: 1. Other severe neurological or psychiatric disorders. 2. History of epilepsy, seizures or convulsions. 3. Patients with any additional cerebral injuries. 4. Metal implantation. 5. Patients cannot be scanned for MRI or cooperated with rTMS and follow up.

Design outcomes

Primary

Measure	Time frame
Freezing of gait questionnaire;	—

Secondary

Measure	Time frame
Parkinson's disease-related scale;Behavioral evalution;Functional connectivity;	—

Countries

China

Contacts

Public ContactGuiyun Cui

Department of Neurology, Affiliated Hospital of Xuzhou Medical University

cuiguiyun-js@163.com+86 13852159170

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026