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The application of brain-specific miRNA in serum exosomes in the prognosis of acute ischemic stroke

The application of serum exosomal has-miR-9-3p, has-miR-124-3p, has-miR-143-3p, and has-miR-98-5p in the prognosis of acute ischemic stroke

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000031677
Enrollment
Unknown
Registered
2020-04-06
Start date
2020-06-01
Completion date
Unknown
Last updated
2020-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute ischemic stroke

Interventions

Upper (lower) quartile group of miRNA:None
miRNA norm group:none

Sponsors

Affiliated Hosipital of Nantong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Patients over 18 years old; 2. The clinical symptoms and signs of patients with cerebral infarction within 72 hours of onset should conform to the WHO definition of stroke; 3. Cases that need to be diagnosed as ischemic stroke by CT or MRI scan, including cerebral thrombosis (atherosclerosis), cerebral embolism (arterial or cardiogenic cerebral embolism) and lacunar infarction; 4. Patients with modified Rankin Scale (MRS) < 2 before onset; 5. Patients willing and able to participate in the study and sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with life expectancy <=1 year; 2. Patients with advanced tumor and dementia.

Design outcomes

Primary

MeasureTime frame
miRNAs;CT or MRI;modified ranking scale;stroke recurrence;other vascular events;—

Countries

China

Contacts

Public ContactQiuhong Ji

Affiliated Hosipital of Nantong University

jiqiuhong@sina.com+86 13962916293

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026