Type B Aortic Dissection
Conditions
Interventions
control group:Life-tech stent graft combined with fenestrated/chimney technique
Experimental group:single-branched stent graft
Sponsors
The Second Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-85 years old, male or non pregnant female; 2. Patients with proximal rupture between 15 mm distal to the left common carotid artery and 20 mm distal to the left subclavian artery; 3. The patients whose dissection is reversed to the dissection of the left subclavian artery; 4. Patients with clinical symptoms related to aortic dissection, such as persistent pain in the chest and back, uncontrolled hypertension, etc; 5. Patients with type B aortic dissection (acute or non acute stage) confirmed by imaging, including penetrating ulcer and intramural hematoma; 6. The imaging examination shows that the patients with hematoma in mediastinum or around the aorta, the involvement of branches and arteries caused the ischemia of important organs, the progress of dissection (the diameter of dissection increased rapidly, >=5mm/3 months), or tumor like dilation (the diameter of aorta >=40mm), and the rupture of dissection; 7. Patients who are willing to complete the clinical study and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with dissection involving zone 0 or zone 1 or ascending aorta dilation; 2. Patients with cardiopulmonary or hepatorenal insufficiency who cannot tolerate tracheal intubation; 3. Patients diagnosed as connective tissue disease; 4. Patients who are allergic to nichrome or iodized contrast agents; 5. Patients with uncontrollable infection; 6. Patients with coagulation dysfunction that is difficult to correct; 7. Patients with severe stenosis of bilateral common femoral artery; 8. Patients who are unable to cooperate with the operation or who have not signed the preoperative informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| perioperative complications; | — |
Secondary
| Measure | Time frame |
|---|---|
| the remodeling of aorta;aorta related events;patency of the LSA and LCCA;3-year and 5-year all cause and aorta related mortality;3-year and 5-year all cause and aorta related mortality;technical success rate; | — |
Countries
China
Contacts
Public ContactYuliang Li
Department of intervention medicine, the Second Hospital of Shandong University
Outcome results
None listed