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To explore the modern scientific connotation of treating knee osteoarthritis with the theory of ''kidney dominants the bone to producing marrow''

To explore the modern scientific connotation of treating knee osteoarthritis with the theory of ''kidney dominants the bone to producing marrow''

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031661
Enrollment
Unknown
Registered
2020-04-06
Start date
2021-01-01
Completion date
Unknown
Last updated
2020-04-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteoarthritis

Interventions

Control:N/A
Experimental group:Bushen Yisui Formula

Sponsors

The First Affiliated Hospital of Zhejiang Chinese Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. to western medicine diagnosis: in 2018, the Chinese society of bone sciences revised the KOA clinical diagnostic criteria; 2. The average age of KOA patients was between 55 and 75 years old and required knee replacement.

Exclusion criteria

Exclusion criteria: 1. With other diseases affecting bone metabolism; 2. With rheumatoid diseases, such as systemic diseases, spondylitis or rheumatoid arthritis; 3. With a history of severe joints.

Design outcomes

Primary

MeasureTime frame
Dnmt3b expression;miRNA-582-5p expression;VAS score;WOMAC score;—

Countries

China

Contacts

Public ContactPeijian Tong

The First Affiliated Hospital of Zhejiang Chinese Medical University

tongpeijian@163.com+86 571-86613684

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026