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A Medical Records Based Study for Mathematical Models for Intraoperative Prediction of Metastasis to Lymph Nodes in the Hilar-intrapulmonary or the Mediastinal Region in Patients with Clinical Stage I Non-Small Cell Lung Cancer

Mathematical Models for Intraoperative Prediction of Metastasis to Lymph Nodes in the Hilar-intrapulmonary or the Mediastinal Region in Patients with Clinical Stage I Non-Small Cell Lung Cancer

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000031620
Enrollment
Unknown
Registered
2020-04-05
Start date
2020-04-15
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small Cell Lung Cancer

Interventions

derivation cohort :Clinicopathological Variables
validation cohort :Clinicopathological Variables

Sponsors

the First Affiliated Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients who had chest and upper abdomen CT scan, brain MRI and whole-body radionuclide bone imaging or tumor PETCT whole-body scan within one week before operation; 2. All patients underwent thoracoscopic radical resection of lung cancer (including lobectomy + systemic lymphadenectomy), and NSCLC was confirmed by postoperative pathology; 3. Those patients who meet the clinical diagnosis of stage I non-small cell lung cancer according to the latest international non-small cell lung cancer staging system (National Comprehensive Cancer Network guidelines, 3rd Edition: non-small cell lung cancer staging).

Exclusion criteria

Exclusion criteria: 1. The diameter of tumor was more than 4cm; 2. The minimum diameter of hilar (inner) and mediastinal lymph nodes was more than 1 cm; 3. There is clinical evidence of suspected intrapulmonary or extrapulmonary distant metastasis; 4. Patients who received neoadjuvant treatment before operation, including chemotherapy and / or radiotherapy. 5. Patients with a history of tuberculosis or other malignancies; 6. Patients who did not meet the criteria of systemic lymphadenectomy (i.e. 10-14 groups of ipsilateral operation, 2-4 and 7-9 groups of right operation, 4-9 groups of left operation) could not be included; 7. Patients with multiple or repeated lung cancer; 8. Postoperative lymph node pathology was diagnosed as a special type of infection or other lymphadenopathy; 9. Patients with incomplete clinicopathological data or whose preoperative examination does not meet the time requirements.

Design outcomes

Primary

MeasureTime frame
Clinicopathological Variables;

Countries

China

Contacts

Public ContactShijiang Zhang

The First Affiliated Hospital of Nanjing Medical University (Jiangsu People's Hospital)

shijiangzhang@hotmail.com+86 13901596786

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026