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Oil-based contrast versus water-based contrast media in the diagnosis of tubal patency at hysterosalpingography: a randomized controlled trial

A randomized controlled trial for oil-based contrast versus water-based contrast media in the diagnosis of tubal patency at hysterosalpingography

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000031612
Enrollment
Unknown
Registered
2020-04-05
Start date
2020-04-05
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

tubal infertility

Interventions

OSCM:oil-based contrast
WSCM:water-based contrast

Sponsors

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20 to 39 years; 2. Spontaneous menstrual cycles (cycle length between 25 and 35 days); 3. Subfertility of at least one year; 4. Chlamydia trachomatis negative of vaginal secretion culture or no Chlamydia infection in the history 5. Low risk for tubal pathology according to the medical history. 6. Valid indication for HSG in the fertility work-up or before intra uterine insemination treatment. 7. Signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Irregular menstrual cycle, less than eight menstrual cycles per year. 2. Endocrino-pathological disease as: Polycystic ovary syndrome, Cushing syndrome, adrenal hyperplasia, hyperprolactinemia, acromegaly, hypothalamic amenorrhea, hypothyroidy, diabetes mellitus, thyroid dysfunction. 3. Known or high risk for tubal pathology, Chlamydia trachomatis positive of vaginal secretion culture, Chlamydia infection in the history. 4. Known contrast (iodine) allergy. 5. Male subfertility defined as a post-wash total motile sperm count < 3 x10^6 spermatozoa/ml. 6. A contra-indication for HSG.

Design outcomes

Primary

MeasureTime frame
ongoing pregnancy rate;

Secondary

MeasureTime frame
clinical pregnancy rate;live birth rate;miscarriage rate;ectopic pregnancy rate;VAS;thyroid function;

Countries

China

Contacts

Public ContactJian Zhang

International Peace Maternity and Child Health Hospital, School of Medicine, Shanghai Jiaotong University

ipmch@foxmail.com+86 18017316017

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 17, 2026