acute pharyngitis and tonsillitis in children
Conditions
Interventions
Sponsors
The First Teaching Hospital of Tianjin University of TCM
Eligibility
Sex/Gender
All
Age
4 Years to 12 Years
Inclusion criteria
Inclusion criteria: 1. Clinical diagnosis of acute pharyngitis/acute tonsillitis; 2. Wind-heat syndrome or heat exuberance in lung and stomach syndrome in TCM; 3. Wong-Baker FACES Pain Rating Scale (WBS) of immediate sore throat >=4 , body temperature =8 years old) shall jointly sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. At the first diagnosis, the child's condition is more serious, and he/she suffers from poor mental state, irritability, headache, or limb muscle pain, and needs antipyretic and analgesic drugs; 2. Children or their parents/caregivers have difficulty understanding or cooperating with the use of WBS; 3. Children with peritonsillar or retropharyngeal abscesses, infectious mononucleosis, and measles and scarlet fever; 4. Children with severe primary diseases of heart, lung, liver, kidney, metabolism, hematopoietic, immune, nervous and spiritual systems; 5. Children with acute laryngitis, otitis media, bronchitis, pneumonia and other complications; 6. Allergic to the experimental drug (KHJS) and its components, and allergic to antipyretic analgesics; 7. Those who had taken acetaminophen, ibuprofen or other antipyretic analgesic within 6 hours before enrollment; 8. Those who the researchers deemed unsuitable for the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the time of producing analgesic effect; | — |
Secondary
| Measure | Time frame |
|---|---|
| duration of analgesic effect;AUC0-3h;rate of producing analgesic effect;rate of disappearance of sore throat ;effective rate of pharyngeal signs;changes of WBS(in days);efficiency of TCM syndrome; | — |
Countries
China
Contacts
Public ContactZhongChengliang
First Teaching Hospital of Tianjin University of TCM
Outcome results
None listed