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The role of BRAF gene detection in the early diagnosis of papillary craniopharyngioma

The role of BRAF gene detection in the early diagnosis of papillary craniopharyngioma

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000031597
Enrollment
Unknown
Registered
2020-04-05
Start date
2020-04-03
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Craniopharyngioma

Interventions

Gold Standard:Post surgery tumor tissue detection of BRAF V600E gene
Index test:Pre-surgery&#32
peripheral&#32
blood&#32
detection&#32
of&#32
V600E

Sponsors

The Seventh Affiliated Hospital, Sun Yat-sen University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
1 Years to 75 Years

Inclusion criteria

Inclusion criteria: (1) Patient aged 1 and 75 years; (2) Patients with papillary craniopharyngioma confirmed by pathological diagnosis after surgery; (3) The patient has no other tumors, especially papillary thyroid carcinoma, small cell lung cancer, melanoma, etc.; (4) Cardiopulmonary function is normal.

Exclusion criteria

Exclusion criteria: (1) Other lesions in the sellar region (eg pituitary tumor / germ cell tumor / inflammation / granuloma, etc.); (2) Surgery has been performed in the saddle area lesion, but no pathological diagnosis after operation; (3) The patient has a tumor in another part; (4) Female patients during pregnancy or lactation; (5) Patients with obvious cardiovascular dysfunction or severe pulmonary disease.

Design outcomes

Primary

MeasureTime frame
BRAF gene;

Countries

China

Contacts

Public ContactFeng Ying

The Seventh Affiliated Hospital, Sun Yat-sen University

fyeagle@163.com+86 13672106839

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026