Effective concentration range of epidural anesthesia for avoiding nerve damage during percutaneous endoscopic transforaminal lumbar discectomy (PELD): a prospective cohort study of biased-coin design (BCD), double blindness, finding the best dose of drugs

Biased-coin design to find the effective concentration range of ropivacaine in epidural anesthesia for percutaneous endoscopic transforaminal lumbar discectomy (PELD)

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000031593

Enrollment

Unknown

Registered

2020-04-05

Start date

2020-05-01

Completion date

Unknown

Last updated

2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lumbar disc disease (LDH)

Interventions

Different doses groups:Biased-coin Random assign different concentrations

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. ASA physical status 1– 3; 2. aged between 41 and 65 years; 3. percutaneous spinal endoscopic surgery

Exclusion criteria

Exclusion criteria: 1) refusal invitation as a volunteer; 2) or have hypersensitivity reactions of local anesthetic; 3) or have contraindications of epidural anesthesia; 4) or have severe systemic diseases; 5) or have intellectual disability or inability to communicate.

Design outcomes

Primary

Measure	Time frame
Response Rate;	—

Countries

China

Contacts

Public ContactBing-Wei Hu

Tongde Hospital of Zhejiang Province

whoboy555@hotmail.com+86 13456976077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026