Lung transplantation
Conditions
Interventions
Two cohorts:tacrolimus alone versus combined use
Sponsors
Wuxi People's Hospital
Eligibility
Sex/Gender
All
Age
1 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Patients who underwent first lung transplantation and treated with oral tacrolimus; (2) Without acute rejection, dialysis treatment, severe gastrointestinal disorders, and untolerate tacrolimus-induced side effects; (3) Good adherence.
Exclusion criteria
Exclusion criteria: 1) combined organ transplantations; 2) unable to be admininstered tacrolimus orally; 3) with acute, severe chronic peptic ulcer and gastrointestinal diseases; 4) with hemodialysis or peritoneal dialysis; 5) have any form of drug abuse and mental disorders; 6) Poor adherence 7) simultaneously participate other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| pharmacokinetic (popPK; | — |
Contacts
Public ContactJingyu Chen
Wuxi Lung Transplant Center, Wuxi people's Hospital affiliated to Nanjing Medical University
Outcome results
None listed