labor
Conditions
Interventions
Preemptive group:Preset epidural catheter, regular contractions and NRS = 5 branches with self-controlled analgesia
control group:Epidural analgesia when the uterine opening is 2cm wide
Sponsors
Jinling Hospital Affiliated to Medical College of Nanjing University
Eligibility
Sex/Gender
Female
Age
22 Years to 35 Years
Inclusion criteria
Inclusion criteria: 1) Subjects voluntarily and signed the informed consent of this trial; 2) Aged 22-35 years; 3) Single, full term, head position pregnancy; 4) ASA I - II; 5) Primiparas; 6) Plan vaginal delivery; 7) Vaginal delivery is possible after evaluation by an obstetrician.
Exclusion criteria
Exclusion criteria: 1) History of previous mental illness, including mental illness diagnosed before or during pregnancy; 2) There are contraindications for epidural puncture, including previous history of central nervous system infection, history of spine and spinal canal disease, systemic infection, skin or soft tissue infection at puncture site, and blood coagulation dysfunction; 3) People who are allergic to drugs used in labor analgesia (lidocaine, ropivacaine, fentanyl); 4) There are comorbidities during pregnancy (gestational diabetes, hypertension, prenatal anemia, chronic pain); 5) People who are dependent on alcohol or opioids; 6) People who have been taking contraceptives for a long time; 7) Those with a long history of hormone therapy; 8) Alcoholics; 9) Suspected or determined to have a history of drug abuse; 10) BMI = 40 kg/m2; 11) Those who participated in other clinical trials in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The percentage of NRS score greater than or equal to 7 for the most severe pain during labor; | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain improvement percentage;Analgesia onset time, NRS score less than 3 points; | — |
Countries
China
Contacts
Public ContactManlin Duan
Jinling Hospital Affiliated to Medical College of Nanjing University
Outcome results
None listed