Acute myocardial infarction
Conditions
Interventions
i-RIC group:PCI, Usual care, and i-RIC program (pre-, per- and post-operative RIC combined with “Internet Plus”-based long-term RIC).
Control group:PCI and Usual care
Sponsors
Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1) Newly developed STEMI according to clinical symptoms, ECG and laboratory confirmation; 2) Adult patients aged >18 yr; 3) Scheduled for PCI; 4) With normal cognitive function indicated by MMSE score >16 and able to cooperate with intervention; 5) Agreed to participate and signed the consent form.
Exclusion criteria
Exclusion criteria: 1) Previous STEMI or non-STEMI; 2) Previous CABG; 3) Previous stroke; 4) Developed thrombolysis within the last 30 days; 5) Cardiogenic shock history; 6) Persistent atrial fibrillation history; 7) Severe complications (e.g. ventricular septal rupture, free wall rupture or acute severe mitral regurgitation) warrant surgical interventions; 8) With peripheral neuropathy, peripheral artery disease, superficial thrombophlebitis or deep vein thrombosis; 9) Estimated survival period less than 12 months due to malignancies or severe systemic diseases; 10) Contraindicated through cardiac MRI; 11) Participated in other trials previously.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiac and cerebrovascular events (MACCE); | — |
Secondary
| Measure | Time frame |
|---|---|
| All-cause mortality (ACM);Myocardial reinfarction rate;Readmission rate for heart failure;Ischemic stroke rate;Unplanned revascularization rate (URR);Plasma concentration of MI-related key biomarkers;Infarct size;Cardiac function;Cardiopulmonary endurance;Health-related quality of life (HRQoL);Total hospital length of stay;Total medical cost;Compliance; | — |
Countries
China
Contacts
Public ContactLu Xiao
Department of Rehabilitation Medicine, the First Affiliated Hospital of Nanjing Medical University
Outcome results
None listed