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Evaluation of prognosis of coma patients with acute brain injury by EEG bispectral index monitoring and FOUR scores

Evaluation of prognosis of coma patients with acute brain injury by EEG bispectral index monitoring and FOUR scores

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000031545
Enrollment
Unknown
Registered
2020-04-04
Start date
2016-06-01
Completion date
Unknown
Last updated
2020-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute brain injury

Interventions

Poor prognosis group:without
Good prognosis group:without

Sponsors

904th Hospital of Joint Logistic Support Force of PLA
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 81 Years

Inclusion criteria

Inclusion criteria: Patients werebeing diagnosed as severe brain injury resulted from various causes such as brain trauma, cerebral vascular disease etc. and had GCS scores <=8.

Exclusion criteria

Exclusion criteria: 1. GCS scores >8; 2. The patient with forehead skin lesions and not being monitored; 3. The patient treated with sedative and muscle relaxant drugs; 4. The patient with Alzheimer's disease caused by various causes in the past; 5. The patient with severe psychiatric symptoms and cannot tolerate BIS sensors; 6. And the patient with continuous monitoring time < 24 hours; 7. Coma patients caused by pulmonary encephalopathy, hepatic encephalopathy, hypoglycemia coma, diabetic ketoacidosis, etc.; 8. Patients with prior seizures were monitored.

Design outcomes

Primary

MeasureTime frame
Bispectral index;Glasgow coma scale,GCS;Full outline of unresponsiveness, FOUR;

Secondary

MeasureTime frame
mean arterial pressure;vasoactive agent application;blood oxygen saturation;artery lactate levels;

Countries

China

Contacts

Public ContactDan Shi

904th Hospital of Joint Logistic Support Force of PLA

stone499@163.com+86 15152261856

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026