acute brain injury
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Patients werebeing diagnosed as severe brain injury resulted from various causes such as brain trauma, cerebral vascular disease etc. and had GCS scores <=8.
Exclusion criteria
Exclusion criteria: 1. GCS scores >8; 2. The patient with forehead skin lesions and not being monitored; 3. The patient treated with sedative and muscle relaxant drugs; 4. The patient with Alzheimer's disease caused by various causes in the past; 5. The patient with severe psychiatric symptoms and cannot tolerate BIS sensors; 6. And the patient with continuous monitoring time < 24 hours; 7. Coma patients caused by pulmonary encephalopathy, hepatic encephalopathy, hypoglycemia coma, diabetic ketoacidosis, etc.; 8. Patients with prior seizures were monitored.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bispectral index;Glasgow coma scale,GCS;Full outline of unresponsiveness, FOUR; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean arterial pressure;vasoactive agent application;blood oxygen saturation;artery lactate levels; | — |
Countries
China
Contacts
904th Hospital of Joint Logistic Support Force of PLA