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A Medical Records Based Study for the Correlation between Angiotensin II Type 1 Receptor Blockers (ARBs) and the Progression and Outcome of Novel Coronavirus Pneumonia (COVID-19)

A Medical Records Based Study for the Correlation between Angiotensin II Type 1 Receptor Blockers (ARBs) and the Progression and Outcome of Novel Coronavirus Pneumonia (COVID-19)

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000031539
Enrollment
Unknown
Registered
2020-04-03
Start date
2020-03-15
Completion date
Unknown
Last updated
2020-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Novel Coronavirus Pneumonia (COVID-19)

Interventions

ARBs Group:Treatment of ARBs
non-ARBs Group:other treatments

Sponsors

Wuhan Women and Children's Health Care Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Patients meet Diagnosis and treatment of novel coronavirus pneumonia (Seventh Edition); 2. Over 18 years old; 3. Patients with hypertension,diabetes and chronic kidney disease were treated with ARBs or other drugs; 4. Complete data; 5. Agree to participate in the study and cooperate with the follow-up.

Exclusion criteria

Exclusion criteria: 1. Missing or incomplete medical records; 2. 28 day follow-up is incompleted; 3. Co-infection with influenza or other viruses; 4. Discontinuation of antihypertensive or chronic kidney disease treatment is more than 48 hours; 5. ACEIs were used during the treatment.

Design outcomes

Primary

MeasureTime frame
Incidence of ARDS;Mortality within 28 days;

Secondary

MeasureTime frame
viral nucleic acid shedding time;Length of hospital stay;Complications;cardiovascular events;CD4+;CD8+;CRP;IL-2;IL-6;PaO2/FiO2;

Countries

China

Contacts

Public ContactZhang Hua-nian

Wuhan Women and Children's Health Care Center

whet_ctr@163.com+86 027 82308909

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026